Important cannabis research conducted by Israeli scientist, Raphael Mechoulam, led to the discovery of the endocannabinoid system. The revelation of this significant biological system has revolutionized our understanding of brain chemistry and the body’s ability to heal.

What Is the Endocannabinoid System?

Humans, pets, and any organism with a vertebra have an endocannabinoid system. The endocannabinoid system is a lipid-based biochemical communicative network that plays an important role in major physiological functions such as pain, mood, appetite, fertility, and more. The endocannabinoid system is primarily comprised of endocannabinoids and cannabinoid receptors. Two endocannabinoids have been identified so far: anandamide and 2-AG. There have also been two cannabinoid receptors identified which are named CB1 and CB2. These cannabinoid receptors are densely located throughout the body with higher concentrations in the brain, nervous system, and immune system. When the body produces endocannabinoids, these compounds attach to corresponding cannabinoid receptors which trigger the built-in inhibitory feedback system. This results in cooling the body’s inflammatory response and nudging all physiological systems towards homeostasis.

Engaging the Endocannabinoid System

The endocannabinoid system can only be engaged by endocannabinoids, phytocannabinoids (plant-derived cannabinoids), and synthetic cannabinoids (lab-synthesized cannabinoids). All three of these compounds are derived from different sources but have the same chemical makeup.

The Endocannabinoid System and CBD

CBD is classified as a phytocannabinoid which can be derived from hemp or marijuana plants. When hemp-derived CBD is introduced to your body, it creates the same harmonic effect caused by endocannabinoids. That’s why CBD may be effective for such a wide range of different conditions among humans and pets.

Learn More About the Endocannabinoid System

Beneficial is a proud CBD advocate and is happy to share all the education regarding the endocannabinoid system. Understanding this important lock and key mechanism can give you a better perspective on cannabinoid therapy and CBD. For more information regarding the endocannabinoid system, please contact us!